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Federal government websites often end in. The site is secure. Preview improvements coming to the PMC website in October Learn More or Try it out now. Correspondence: ti. Patient sera were studied with Luminex standard and C1Q test. One of the two patients enrolled for the first transplant received the kidney from a living donor.
The patient who received the kidney from a living donor did not show evidence of DSA in the sera nor in the biopsy specimens. Correspondence: rf. These results prompt further study on larger cohorts of LTxR. Correspondence: moc. Kidney transplantation represents the best care for patients with severe and irreversible renal failure and provides more treatment opportunities than dialysis. In our region, before 1 October , the effective date of the single regional list, the kidneys were assigned according to a specific shift and each CT was authorized to choose between a group of 5 patients with their own selection criteria, determining a different access to care and less patient protection.
With the single regional list, however, the same criteria are applied for all centers and it has made it possible to guarantee a better preliminary assessment for hyperimmunized patients and, above all, it guarantees all patients a fairer access to organ allocation.
The search for a fully matched kidney increases time on the waiting list. Here we present a single clinical case, from the regional waiting list for kidney transplantation. In the patient was included in the regional urgent list due to exhaustion of the vascular bed and impossibility to perform peritoneal dialysis. Unfortunately, all the crossmatches performed with all cadaveric donor available in Sicily resulted positive and the patient was excluded. Biopsy performed two months after transplantation, was identical to the one performed at the time of transplantation and no damage due to humoral rejection was detected, but only cytotoxic damage, probably due to pharmacological treatment.
Every clinical evaluation is premature, but this case represents a positive outcome of the application of the single regional list.